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Methylation analysis of histone H4K12ac-associated promoters in sperm of healthy donors and subfertile patients

BACKGROUND: Histone to protamine exchange and the hyperacetylation of the remaining histones are hallmarks of spermiogenesis. Acetylation of histone H4 at lysine 12 (H4K12ac) was observed prior to full decondensation of sperm chromatin after fertilization suggesting an important role for the regulat...

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Detalles Bibliográficos
Autores principales:	Vieweg, Markus, Dvorakova-Hortova, Katerina, Dudkova, Barbora, Waliszewski, Przemyslaw, Otte, Marie, Oels, Berthold, Hajimohammad, Amir, Turley, Heiko, Schorsch, Martin, Schuppe, Hans-Christian, Weidner, Wolfgang, Steger, Klaus, Paradowska-Dogan, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372182/ https://www.ncbi.nlm.nih.gov/pubmed/25806092 http://dx.doi.org/10.1186/s13148-015-0058-4

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