Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature

INTRODUCTION: Neurofibromatosis type 1, also known as Von Recklinghausen’s disease, is a rare neuroectodermal disease that mainly affects the skin and the nervous system. Patients with neurofibromatosis type 1 have a higher risk of developing various types of cancers, especially tumors derived from...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalil, Jihane, Afif, Mohamed, Elkacemi, Hanan, Benoulaid, Meryem, Kebdani, Tayeb, Benjaafar, Noureddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372231/
https://www.ncbi.nlm.nih.gov/pubmed/25889501
http://dx.doi.org/10.1186/s13256-015-0533-8
_version_ 1782363144934391808
author Khalil, Jihane
Afif, Mohamed
Elkacemi, Hanan
Benoulaid, Meryem
Kebdani, Tayeb
Benjaafar, Noureddine
author_facet Khalil, Jihane
Afif, Mohamed
Elkacemi, Hanan
Benoulaid, Meryem
Kebdani, Tayeb
Benjaafar, Noureddine
author_sort Khalil, Jihane
collection PubMed
description INTRODUCTION: Neurofibromatosis type 1, also known as Von Recklinghausen’s disease, is a rare neuroectodermal disease that mainly affects the skin and the nervous system. Patients with neurofibromatosis type 1 have a higher risk of developing various types of cancers, especially tumors derived from the embryogenic neural crest. However, its association with breast cancer has seldom been reported. CASE PRESENTATION: We report the cases of three white Arabic women diagnosed with neurofibromatosis type 1, with a median age of 40-years-old (range: 39 to 43), who sought treatment at our centre for breast cancer. CONCLUSIONS: The association between neurofibromatosis type 1 and breast cancer is uncommon. In our case series we readdress this association through a literature review.
format Online
Article
Text
id pubmed-4372231
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-43722312015-03-25 Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature Khalil, Jihane Afif, Mohamed Elkacemi, Hanan Benoulaid, Meryem Kebdani, Tayeb Benjaafar, Noureddine J Med Case Rep Case Report INTRODUCTION: Neurofibromatosis type 1, also known as Von Recklinghausen’s disease, is a rare neuroectodermal disease that mainly affects the skin and the nervous system. Patients with neurofibromatosis type 1 have a higher risk of developing various types of cancers, especially tumors derived from the embryogenic neural crest. However, its association with breast cancer has seldom been reported. CASE PRESENTATION: We report the cases of three white Arabic women diagnosed with neurofibromatosis type 1, with a median age of 40-years-old (range: 39 to 43), who sought treatment at our centre for breast cancer. CONCLUSIONS: The association between neurofibromatosis type 1 and breast cancer is uncommon. In our case series we readdress this association through a literature review. BioMed Central 2015-03-19 /pmc/articles/PMC4372231/ /pubmed/25889501 http://dx.doi.org/10.1186/s13256-015-0533-8 Text en © Khalil et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Khalil, Jihane
Afif, Mohamed
Elkacemi, Hanan
Benoulaid, Meryem
Kebdani, Tayeb
Benjaafar, Noureddine
Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
title Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
title_full Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
title_fullStr Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
title_full_unstemmed Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
title_short Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
title_sort breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372231/
https://www.ncbi.nlm.nih.gov/pubmed/25889501
http://dx.doi.org/10.1186/s13256-015-0533-8
work_keys_str_mv AT khaliljihane breastcancerassociatedwithneurofibromatosistype1acaseseriesandreviewoftheliterature
AT afifmohamed breastcancerassociatedwithneurofibromatosistype1acaseseriesandreviewoftheliterature
AT elkacemihanan breastcancerassociatedwithneurofibromatosistype1acaseseriesandreviewoftheliterature
AT benoulaidmeryem breastcancerassociatedwithneurofibromatosistype1acaseseriesandreviewoftheliterature
AT kebdanitayeb breastcancerassociatedwithneurofibromatosistype1acaseseriesandreviewoftheliterature
AT benjaafarnoureddine breastcancerassociatedwithneurofibromatosistype1acaseseriesandreviewoftheliterature

Ejemplares similares