Retinoic Acid Is Essential for Th1 Cell Lineage Stability and Prevents Transition to a Th17 Cell Program

CD4(+) T cells differentiate into phenotypically distinct T helper cells upon antigenic stimulation. Regulation of plasticity between these CD4(+) T-cell lineages is critical for immune homeostasis and prevention of autoimmune disease. However, the factors that regulate lineage stability are largely...

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Detalles Bibliográficos
Autores principales: Brown, Chrysothemis C., Esterhazy, Daria, Sarde, Aurelien, London, Mariya, Pullabhatla, Venu, Osma-Garcia, Ines, al-Bader, Raya, Ortiz, Carla, Elgueta, Raul, Arno, Matthew, de Rinaldis, Emanuele, Mucida, Daniel, Lord, Graham M., Noelle, Randolph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372260/
https://www.ncbi.nlm.nih.gov/pubmed/25769610
http://dx.doi.org/10.1016/j.immuni.2015.02.003

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