Sensitization of P2X3 receptors by cystathionine β-synthetase mediates persistent pain hypersensitivity in a rat model of lumbar disc herniation

Lumbar disc herniation (LDH) is a major cause of discogenic low back pain and sciatica, but the underlying mechanisms remain largely unknown. Hydrogen sulfide (H(2)S) is becoming recognized for its involvement in a wide variety of processes including inflammation and nociception. The present study w...

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Detalles Bibliográficos
Autores principales: Wang, Qianliang, Zhu, Hongyan, Zou, Kang, Yuan, Bo, Zhou, You-Lang, Jiang, Xinghong, Yan, Jun, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372268/
https://www.ncbi.nlm.nih.gov/pubmed/25885215
http://dx.doi.org/10.1186/s12990-015-0012-7

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