Cargando…
Mycobacterium marinum infection: a case report
The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the fina...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372314/ https://www.ncbi.nlm.nih.gov/pubmed/25806076 http://dx.doi.org/10.1186/s40409-015-0008-9 |
_version_ | 1782363158836412416 |
---|---|
author | Sette, Christiane Salgado Wachholz, Patrick Alexander Masuda, Paula Yoshiko da Costa Figueira, Renata Borges Fortes de Oliveira Mattar, Fernanda Rodrigues Ura, Deise Godoy |
author_facet | Sette, Christiane Salgado Wachholz, Patrick Alexander Masuda, Paula Yoshiko da Costa Figueira, Renata Borges Fortes de Oliveira Mattar, Fernanda Rodrigues Ura, Deise Godoy |
author_sort | Sette, Christiane Salgado |
collection | PubMed |
description | The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group. |
format | Online Article Text |
id | pubmed-4372314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43723142015-03-25 Mycobacterium marinum infection: a case report Sette, Christiane Salgado Wachholz, Patrick Alexander Masuda, Paula Yoshiko da Costa Figueira, Renata Borges Fortes de Oliveira Mattar, Fernanda Rodrigues Ura, Deise Godoy J Venom Anim Toxins Incl Trop Dis Case Report The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group. BioMed Central 2015-03-20 /pmc/articles/PMC4372314/ /pubmed/25806076 http://dx.doi.org/10.1186/s40409-015-0008-9 Text en © Sette et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Sette, Christiane Salgado Wachholz, Patrick Alexander Masuda, Paula Yoshiko da Costa Figueira, Renata Borges Fortes de Oliveira Mattar, Fernanda Rodrigues Ura, Deise Godoy Mycobacterium marinum infection: a case report |
title | Mycobacterium marinum infection: a case report |
title_full | Mycobacterium marinum infection: a case report |
title_fullStr | Mycobacterium marinum infection: a case report |
title_full_unstemmed | Mycobacterium marinum infection: a case report |
title_short | Mycobacterium marinum infection: a case report |
title_sort | mycobacterium marinum infection: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372314/ https://www.ncbi.nlm.nih.gov/pubmed/25806076 http://dx.doi.org/10.1186/s40409-015-0008-9 |
work_keys_str_mv | AT settechristianesalgado mycobacteriummarinuminfectionacasereport AT wachholzpatrickalexander mycobacteriummarinuminfectionacasereport AT masudapaulayoshiko mycobacteriummarinuminfectionacasereport AT dacostafigueirarenataborgesfortes mycobacteriummarinuminfectionacasereport AT deoliveiramattarfernandarodrigues mycobacteriummarinuminfectionacasereport AT uradeisegodoy mycobacteriummarinuminfectionacasereport |