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Mycobacterium marinum infection: a case report

The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the fina...

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Autores principales: Sette, Christiane Salgado, Wachholz, Patrick Alexander, Masuda, Paula Yoshiko, da Costa Figueira, Renata Borges Fortes, de Oliveira Mattar, Fernanda Rodrigues, Ura, Deise Godoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372314/
https://www.ncbi.nlm.nih.gov/pubmed/25806076
http://dx.doi.org/10.1186/s40409-015-0008-9
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author Sette, Christiane Salgado
Wachholz, Patrick Alexander
Masuda, Paula Yoshiko
da Costa Figueira, Renata Borges Fortes
de Oliveira Mattar, Fernanda Rodrigues
Ura, Deise Godoy
author_facet Sette, Christiane Salgado
Wachholz, Patrick Alexander
Masuda, Paula Yoshiko
da Costa Figueira, Renata Borges Fortes
de Oliveira Mattar, Fernanda Rodrigues
Ura, Deise Godoy
author_sort Sette, Christiane Salgado
collection PubMed
description The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group.
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spelling pubmed-43723142015-03-25 Mycobacterium marinum infection: a case report Sette, Christiane Salgado Wachholz, Patrick Alexander Masuda, Paula Yoshiko da Costa Figueira, Renata Borges Fortes de Oliveira Mattar, Fernanda Rodrigues Ura, Deise Godoy J Venom Anim Toxins Incl Trop Dis Case Report The infection by Mycobacterium marinum in humans is relatively uncommon. When it occurs, it mainly affects the skin, usually with a chronic, indolent and benign evolution. The diagnosis requires a high index of suspicion, and a significant delay may be observed between the first symptoms to the final diagnosis. This present case reports a M. marinum infection in an immunocompetent patient that had a chronic undiagnosed injury on the dominant hand for at least five years. The patient had several medical consultations, without proper suspicion, hampering adequate diagnostic investigation. Histopathology detected tuberculoid granulomas, but showed no acid-fast bacilli. The culture in appropriate medium and the polymerase chain reaction-restriction enzyme analysis (PRA)-hsp65 confirmed the diagnosis. Treatment with clarithromycin (1 g/day) for three months was effective. Although uncommon, this infection is a contact zoonosis. Therefore, it is important for clinicians to be aware of this diagnosis and properly guide preventable measures to professionals that are in risk group. BioMed Central 2015-03-20 /pmc/articles/PMC4372314/ /pubmed/25806076 http://dx.doi.org/10.1186/s40409-015-0008-9 Text en © Sette et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sette, Christiane Salgado
Wachholz, Patrick Alexander
Masuda, Paula Yoshiko
da Costa Figueira, Renata Borges Fortes
de Oliveira Mattar, Fernanda Rodrigues
Ura, Deise Godoy
Mycobacterium marinum infection: a case report
title Mycobacterium marinum infection: a case report
title_full Mycobacterium marinum infection: a case report
title_fullStr Mycobacterium marinum infection: a case report
title_full_unstemmed Mycobacterium marinum infection: a case report
title_short Mycobacterium marinum infection: a case report
title_sort mycobacterium marinum infection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372314/
https://www.ncbi.nlm.nih.gov/pubmed/25806076
http://dx.doi.org/10.1186/s40409-015-0008-9
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