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Regulatory Components of the Alternative Complement Pathway in Endothelial Cell Cytoplasm, Factor H and Factor I, Are Not Packaged in Weibel-Palade Bodies

It was recently reported that factor H, a regulatory component of the alternative complement pathway, is stored with von Willebrand factor (VWF) in the Weibel-Palade bodies of endothelial cells. If this were to be the case, it would have therapeutic importance for patients with the atypical hemolyti...

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Detalles Bibliográficos
Autores principales: Turner, Nancy A., Sartain, Sarah E., Hui, Shiu-Ki, Moake, Joel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372330/
https://www.ncbi.nlm.nih.gov/pubmed/25803806
http://dx.doi.org/10.1371/journal.pone.0121994