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Blockade of the SNARE Protein Syntaxin 1 Inhibits Glioblastoma Tumor Growth
Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a median overall survival of 15 months from diagnosis despite of the treatment. SNARE proteins mediate membrane fusion events in cells and are essential for many cellular processes including exocytosis and n...
Autores principales: | Ulloa, Fausto, Gonzàlez-Juncà, Alba, Meffre, Delphine, Barrecheguren, Pablo José, Martínez-Mármol, Ramón, Pazos, Irene, Olivé, Núria, Cotrufo, Tiziana, Seoane, Joan, Soriano, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372377/ https://www.ncbi.nlm.nih.gov/pubmed/25803850 http://dx.doi.org/10.1371/journal.pone.0119707 |
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