Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease

This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients attending the memory clinic: cases of mild cognitive impairment (MCI; n = 16), cases of MCI who upon subsequent follow-up developed Alzheime...

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Detalles Bibliográficos
Autores principales: Graham, Stewart F., Chevallier, Olivier P., Elliott, Christopher T., Hölscher, Christian, Johnston, Janet, McGuinness, Bernadette, Kehoe, Patrick G., Passmore, Anthony Peter, Green, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372431/
https://www.ncbi.nlm.nih.gov/pubmed/25803028
http://dx.doi.org/10.1371/journal.pone.0119452

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