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Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease
This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients attending the memory clinic: cases of mild cognitive impairment (MCI; n = 16), cases of MCI who upon subsequent follow-up developed Alzheime...
Autores principales: | Graham, Stewart F., Chevallier, Olivier P., Elliott, Christopher T., Hölscher, Christian, Johnston, Janet, McGuinness, Bernadette, Kehoe, Patrick G., Passmore, Anthony Peter, Green, Brian D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372431/ https://www.ncbi.nlm.nih.gov/pubmed/25803028 http://dx.doi.org/10.1371/journal.pone.0119452 |
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