Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR1

Induced pluripotent stem (iPS) cells provide powerful tools for studying disease mechanisms and developing therapies for diseases. The 8p11 myeloproliferative syndrome (EMS) is an aggressive chronic myeloproliferative disorder (MPD) that is caused by constitutive activation of fibroblast growth fact...

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Detalles Bibliográficos
Autores principales: Yamamoto, Shohei, Otsu, Makoto, Matsuzaka, Emiko, Konishi, Chieko, Takagi, Haruna, Hanada, Sachiyo, Mochizuki, Shinji, Nakauchi, Hiromitsu, Imai, Kohzoh, Tsuji, Kohichiro, Ebihara, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372437/
https://www.ncbi.nlm.nih.gov/pubmed/25803811
http://dx.doi.org/10.1371/journal.pone.0120841

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