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Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9
ZFN, TALENs and CRISPR/Cas9 system have been used to generate point mutations and large fragment deletions and insertions in genomic modifications. CRISPR/Cas9 system is the most flexible and fast developing technology that has been extensively used to make mutations in all kinds of organisms. Howev...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372442/ https://www.ncbi.nlm.nih.gov/pubmed/25803037 http://dx.doi.org/10.1371/journal.pone.0120396 |