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Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9

ZFN, TALENs and CRISPR/Cas9 system have been used to generate point mutations and large fragment deletions and insertions in genomic modifications. CRISPR/Cas9 system is the most flexible and fast developing technology that has been extensively used to make mutations in all kinds of organisms. Howev...

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Detalles Bibliográficos
Autores principales: Zhang, Luqing, Jia, Ruirui, Palange, Norberto J., Satheka, Achim Cchitvsanzwhoh, Togo, Jacques, An, Yao, Humphrey, Mabwi, Ban, Luying, Ji, Yan, Jin, Honghong, Feng, Xuechao, Zheng, Yaowu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372442/
https://www.ncbi.nlm.nih.gov/pubmed/25803037
http://dx.doi.org/10.1371/journal.pone.0120396