Human CD8(+) T-cells Recognizing Peptides from Mycobacterium tuberculosis (Mtb) Presented by HLA-E Have an Unorthodox Th2-like, Multifunctional, Mtb Inhibitory Phenotype and Represent a Novel Human T-cell Subset

Mycobacterial antigens are not exclusively presented to T-cells by classical HLA-class Ia and HLA-class II molecules, but also through alternative antigen presentation molecules such as CD1a/b/c, MR1 and HLA-E. We recently described mycobacterial peptides that are presented in HLA-E and recognized b...

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Detalles Bibliográficos
Autores principales: van Meijgaarden, Krista E., Haks, Mariëlle C., Caccamo, Nadia, Dieli, Francesco, Ottenhoff, Tom H. M., Joosten, Simone A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372528/
https://www.ncbi.nlm.nih.gov/pubmed/25803478
http://dx.doi.org/10.1371/journal.ppat.1004671

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