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Effect of In Vitro Syncytium Formation on the Severity of Human Metapneumovirus Disease in a Murine Model
Human metapneumovirus (HMPV) is an important cause of acute respiratory tract infections (ARTI) in children, elderly individuals and immunocompromised patients. In vitro, different HMPV strains can induce variable cytopathic effects ranging from large multinucleated syncytia to focal cell rounding....
Autores principales: | Aerts, Laetitia, Cavanagh, Marie-Hélène, Dubois, Julia, Carbonneau, Julie, Rhéaume, Chantal, Lavigne, Sophie, Couture, Christian, Hamelin, Marie-Ève, Boivin, Guy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372586/ https://www.ncbi.nlm.nih.gov/pubmed/25803584 http://dx.doi.org/10.1371/journal.pone.0120283 |
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