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Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis
Objective: Bone scintigraphy is a highly sensitive method in the evaluation of sacroiliitis. Aim of this study is firstly to evaluate interobserver variation of partial and whole sacroiliac indicis, secondly investigation of clinical importance of these indicis in the diagnosis of sacroiliitis. Meth...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372772/ https://www.ncbi.nlm.nih.gov/pubmed/25800592 http://dx.doi.org/10.4274/mirt.40427 |
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author | Koç, Zehra Pınar Cengiz, Arzu Kin Aydın, Funda Samancı, Nehir Yazısız, Veli Koca, Süleyman Serdar Karayalçın, Binnur |
author_facet | Koç, Zehra Pınar Cengiz, Arzu Kin Aydın, Funda Samancı, Nehir Yazısız, Veli Koca, Süleyman Serdar Karayalçın, Binnur |
author_sort | Koç, Zehra Pınar |
collection | PubMed |
description | Objective: Bone scintigraphy is a highly sensitive method in the evaluation of sacroiliitis. Aim of this study is firstly to evaluate interobserver variation of partial and whole sacroiliac indicis, secondly investigation of clinical importance of these indicis in the diagnosis of sacroiliitis. Methods: Fourty-six subjects (24 female: 35.4±11.9; 22 male: 43.1±12.4) without sacroiliitis 45 subjects with low back pain (33 female: 43.3±11.5, 11 male: 35.5±17.2) were included in the study. For right (R) and left (L) whole indices (WSI) irregular region of interest (ROI), for partial indices superior (S) and inferior (I) rectangular ROI were used. For background activity, rectangular ROI was drawn from the sacral region. Indices were calculated from ratio of average counts of sacroiliac and background regions. Two independent observers calculated sacroiliac indices. Interobserver agreement was evaluated by Pearson analysis. Results: There was no significant interobserver difference (p>0.05). Significant correlation existed between all calculated indices. Among 45 patients with suspicion of sacroiliitis 15 had final diagnosis of sacroiliitis and all of the Tc-99m methilenediphosphonate planar and SPECT bone scintigraphy results of these patients were concordant with sacroiliitis. There were 8 false positive results in other 30 patients. Seven of these eight patients had normal index values. If the scintigraphy would be evaluated in conjuction with indicis the specificity would increase from 73% to 97% but sensitivity decreases from 100% to 80%. There was significant correlation between the observers calculated indicis (p<0.001). Conclusion: Superior and inferior sacroiliac index values can be used with confidence. If we use sacroiliac index values to confirm positive results; index values can increase the specificity of bone scintigraphy. |
format | Online Article Text |
id | pubmed-4372772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-43727722015-03-31 Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis Koç, Zehra Pınar Cengiz, Arzu Kin Aydın, Funda Samancı, Nehir Yazısız, Veli Koca, Süleyman Serdar Karayalçın, Binnur Mol Imaging Radionucl Ther Original Article Objective: Bone scintigraphy is a highly sensitive method in the evaluation of sacroiliitis. Aim of this study is firstly to evaluate interobserver variation of partial and whole sacroiliac indicis, secondly investigation of clinical importance of these indicis in the diagnosis of sacroiliitis. Methods: Fourty-six subjects (24 female: 35.4±11.9; 22 male: 43.1±12.4) without sacroiliitis 45 subjects with low back pain (33 female: 43.3±11.5, 11 male: 35.5±17.2) were included in the study. For right (R) and left (L) whole indices (WSI) irregular region of interest (ROI), for partial indices superior (S) and inferior (I) rectangular ROI were used. For background activity, rectangular ROI was drawn from the sacral region. Indices were calculated from ratio of average counts of sacroiliac and background regions. Two independent observers calculated sacroiliac indices. Interobserver agreement was evaluated by Pearson analysis. Results: There was no significant interobserver difference (p>0.05). Significant correlation existed between all calculated indices. Among 45 patients with suspicion of sacroiliitis 15 had final diagnosis of sacroiliitis and all of the Tc-99m methilenediphosphonate planar and SPECT bone scintigraphy results of these patients were concordant with sacroiliitis. There were 8 false positive results in other 30 patients. Seven of these eight patients had normal index values. If the scintigraphy would be evaluated in conjuction with indicis the specificity would increase from 73% to 97% but sensitivity decreases from 100% to 80%. There was significant correlation between the observers calculated indicis (p<0.001). Conclusion: Superior and inferior sacroiliac index values can be used with confidence. If we use sacroiliac index values to confirm positive results; index values can increase the specificity of bone scintigraphy. Galenos Publishing 2015-02 2015-02-15 /pmc/articles/PMC4372772/ /pubmed/25800592 http://dx.doi.org/10.4274/mirt.40427 Text en © Molecular Imaging and Radionuclide Therapy, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Koç, Zehra Pınar Cengiz, Arzu Kin Aydın, Funda Samancı, Nehir Yazısız, Veli Koca, Süleyman Serdar Karayalçın, Binnur Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis |
title | Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis |
title_full | Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis |
title_fullStr | Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis |
title_full_unstemmed | Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis |
title_short | Sacroiliac Indicis Increase the Specificity of Bone Scintigraphy in the Diagnosis of Sacroiliitis |
title_sort | sacroiliac indicis increase the specificity of bone scintigraphy in the diagnosis of sacroiliitis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372772/ https://www.ncbi.nlm.nih.gov/pubmed/25800592 http://dx.doi.org/10.4274/mirt.40427 |
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