Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

Histone dacetylases (HDACs) are a group of enzymes that remove acetyl groups from histones and regulate expression of tumor suppressor genes. They are implicated in many human diseases, especially cancer, making them a promising therapeutic target for treatment of the latter by developing a wide var...

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Detalles Bibliográficos
Autores principales: Mottamal, Madhusoodanan, Zheng, Shilong, Huang, Tien L., Wang, Guangdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372801/
https://www.ncbi.nlm.nih.gov/pubmed/25738536
http://dx.doi.org/10.3390/molecules20033898

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