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Effects of the lipid regulating drug clofibric acid on PPARα-regulated gene transcript levels in common carp (Cyprinus carpio) at pharmacological and environmental exposure levels

In mammals, the peroxisome proliferator-activated receptor α (PPARα) plays a key role in regulating various genes involved in lipid metabolism, bile acid synthesis and cholesterol homeostasis, and is activated by a diverse group of compounds collectively termed peroxisome proliferators (PPs). Specif...

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Detalles Bibliográficos
Autores principales: Corcoran, Jenna, Winter, Matthew J., Lange, Anke, Cumming, Rob, Owen, Stewart F., Tyler, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North Holland Biomedical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372818/
https://www.ncbi.nlm.nih.gov/pubmed/25749508
http://dx.doi.org/10.1016/j.aquatox.2015.01.033

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