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Effects of the lipid regulating drug clofibric acid on PPARα-regulated gene transcript levels in common carp (Cyprinus carpio) at pharmacological and environmental exposure levels
In mammals, the peroxisome proliferator-activated receptor α (PPARα) plays a key role in regulating various genes involved in lipid metabolism, bile acid synthesis and cholesterol homeostasis, and is activated by a diverse group of compounds collectively termed peroxisome proliferators (PPs). Specif...
Autores principales: | Corcoran, Jenna, Winter, Matthew J., Lange, Anke, Cumming, Rob, Owen, Stewart F., Tyler, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North Holland Biomedical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372818/ https://www.ncbi.nlm.nih.gov/pubmed/25749508 http://dx.doi.org/10.1016/j.aquatox.2015.01.033 |
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