Cargando…

Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India

INTRODUCTION: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. OBJECTIVES: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care hospital...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Pravesh, Singal, Archana, Pandhi, Deepika, Das, Shukla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372907/
https://www.ncbi.nlm.nih.gov/pubmed/25814703
http://dx.doi.org/10.4103/0019-5154.152511
_version_ 1782363252423917568
author Yadav, Pravesh
Singal, Archana
Pandhi, Deepika
Das, Shukla
author_facet Yadav, Pravesh
Singal, Archana
Pandhi, Deepika
Das, Shukla
author_sort Yadav, Pravesh
collection PubMed
description INTRODUCTION: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. OBJECTIVES: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care hospital. MATERIALS AND METHODS: Hundred consecutive patients of KOH and culture-positive dermatophyte toenail OM were subjected to detailed history, clinical examination and investigations. RESULTS: Maximum number of patients (40%) belonged to 31-45 years age group and there was a male preponderance (M:F = 6.7:1). The mean duration of disease was 54 months. Thirty-three patients had fingernail involvement in addition to the toenail OM and 37% had co-existent cutaneous dermatophyte infection. Discoloration was the most common symptom (98%). Ninety-four (94%) patients had distal lateral subungual onychomycosis (DSLO) while two had superficial onychomycosis (SO) and only one had proximal superficial onychomycosis (PSO). Trichophyton interdigitale was the most common etiological agent (61%) followed by Trichophyton rubrum and Trichophyton verrucosum. CONCLUSIONS: Toenail OM is more common in males. DSLO was the most common clinical variant and T. interdigitale the most common etiological fungus responsible for toenail OM in our region. The importance of early diagnosis and treatment is highlighted as long-standing toenail OM predisposes to fingernail onychomycosis and recurrent tinea pedis.
format Online
Article
Text
id pubmed-4372907
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-43729072015-03-26 Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India Yadav, Pravesh Singal, Archana Pandhi, Deepika Das, Shukla Indian J Dermatol Original Article INTRODUCTION: There is a constant need to define the epidemiological and mycological characteristics of onychomycosis (OM) for optimal management strategies. OBJECTIVES: To define the epidemiological and mycological characteristics of patients with dermatophyte toenail OM in a tertiary care hospital. MATERIALS AND METHODS: Hundred consecutive patients of KOH and culture-positive dermatophyte toenail OM were subjected to detailed history, clinical examination and investigations. RESULTS: Maximum number of patients (40%) belonged to 31-45 years age group and there was a male preponderance (M:F = 6.7:1). The mean duration of disease was 54 months. Thirty-three patients had fingernail involvement in addition to the toenail OM and 37% had co-existent cutaneous dermatophyte infection. Discoloration was the most common symptom (98%). Ninety-four (94%) patients had distal lateral subungual onychomycosis (DSLO) while two had superficial onychomycosis (SO) and only one had proximal superficial onychomycosis (PSO). Trichophyton interdigitale was the most common etiological agent (61%) followed by Trichophyton rubrum and Trichophyton verrucosum. CONCLUSIONS: Toenail OM is more common in males. DSLO was the most common clinical variant and T. interdigitale the most common etiological fungus responsible for toenail OM in our region. The importance of early diagnosis and treatment is highlighted as long-standing toenail OM predisposes to fingernail onychomycosis and recurrent tinea pedis. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4372907/ /pubmed/25814703 http://dx.doi.org/10.4103/0019-5154.152511 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yadav, Pravesh
Singal, Archana
Pandhi, Deepika
Das, Shukla
Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India
title Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India
title_full Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India
title_fullStr Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India
title_full_unstemmed Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India
title_short Clinico-Mycological Study of Dermatophyte Toenail Onychomycosis in New Delhi, India
title_sort clinico-mycological study of dermatophyte toenail onychomycosis in new delhi, india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372907/
https://www.ncbi.nlm.nih.gov/pubmed/25814703
http://dx.doi.org/10.4103/0019-5154.152511
work_keys_str_mv AT yadavpravesh clinicomycologicalstudyofdermatophytetoenailonychomycosisinnewdelhiindia
AT singalarchana clinicomycologicalstudyofdermatophytetoenailonychomycosisinnewdelhiindia
AT pandhideepika clinicomycologicalstudyofdermatophytetoenailonychomycosisinnewdelhiindia
AT dasshukla clinicomycologicalstudyofdermatophytetoenailonychomycosisinnewdelhiindia