In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAF(V600E) in melanoma

BACKGROUND: The recurrent BRAF driver mutation V600E (BRAF(V600E)) is currently one of the most clinically relevant mutations in melanoma. However, the genome-wide transcriptional and epigenetic dysregulations induced by BRAF(V600E) are still unclear. The investigation of this driver mutation’s func...

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Detalles Bibliográficos
Autores principales: Guo, Xingyi, Xu, Yaomin, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373107/
https://www.ncbi.nlm.nih.gov/pubmed/25890285
http://dx.doi.org/10.1186/s12943-015-0328-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373107/
https://www.ncbi.nlm.nih.gov/pubmed/25890285
http://dx.doi.org/10.1186/s12943-015-0328-y

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