Cargando…
In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAF(V600E) in melanoma
BACKGROUND: The recurrent BRAF driver mutation V600E (BRAF(V600E)) is currently one of the most clinically relevant mutations in melanoma. However, the genome-wide transcriptional and epigenetic dysregulations induced by BRAF(V600E) are still unclear. The investigation of this driver mutation’s func...
Autores principales: | Guo, Xingyi, Xu, Yaomin, Zhao, Zhongming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373107/ https://www.ncbi.nlm.nih.gov/pubmed/25890285 http://dx.doi.org/10.1186/s12943-015-0328-y |
Ejemplares similares
-
BRAF(V600E) protein expression and outcome from BRAF inhibitor treatment in BRAF(V600E) metastatic melanoma
por: Wilmott, J S, et al.
Publicado: (2013) -
Immunohistochemical BRAF V600E Expression and Intratumor BRAF V600E Heterogeneity in Acral Melanoma: Implication in Melanoma-Specific Survival
por: Ito, Takamichi, et al.
Publicado: (2020) -
Epigenetic inhibitors eliminate senescent melanoma BRAFV600E cells that survive long-term BRAF inhibition
por: Rowdo, Florencia Paula Madorsky, et al.
Publicado: (2020) -
Differential responsiveness to BRAF inhibitors of melanoma cell lines BRAF V600E-mutated
por: Al Hashmi, Muna, et al.
Publicado: (2020) -
Multifocal BRAF(V600E)-Mutated Melanoma in situ on the Foot
por: Iwama, Eimei, et al.
Publicado: (2015)