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Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus

Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing functions (GliA, GliR) of transcription factors Gli2 and Gli3. This balance—the Shh-Gli code—is species- and context-dependent and has been elucidated for the mouse s...

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Detalles Bibliográficos
Autores principales: Haddad-Tóvolli, Roberta, Paul, Fabian A., Zhang, Yuanfeng, Zhou, Xunlei, Theil, Thomas, Puelles, Luis, Blaess, Sandra, Alvarez-Bolado, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373379/
https://www.ncbi.nlm.nih.gov/pubmed/25859185
http://dx.doi.org/10.3389/fnana.2015.00034