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SNES: single nucleus exome sequencing

Single-cell genome sequencing methods are challenged by poor physical coverage and high error rates, making it difficult to distinguish real biological variants from technical artifacts. To address this problem, we developed a method called SNES that combines flow-sorting of single G1/0 or G2/M nucl...

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Detalles Bibliográficos
Autores principales:	Leung, Marco L, Wang, Yong, Waters, Jill, Navin, Nicholas E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373516/ https://www.ncbi.nlm.nih.gov/pubmed/25853327 http://dx.doi.org/10.1186/s13059-015-0616-2

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