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Glycosyl Phosphatidylinositol Anchor Biosynthesis Is Essential for Maintaining Epithelial Integrity during Caenorhabditis elegans Embryogenesis

Glycosylphosphatidylinositol (GPI) is a post-translational modification resulting in the attachment of modified proteins to the outer leaflet of the plasma membrane. Tissue culture experiments have shown GPI-anchored proteins (GPI-APs) to be targeted to the apical membrane of epithelial cells. Howev...

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Detalles Bibliográficos
Autores principales: Budirahardja, Yemima, Doan, Thang Dinh, Zaidel-Bar, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373761/
https://www.ncbi.nlm.nih.gov/pubmed/25807459
http://dx.doi.org/10.1371/journal.pgen.1005082

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