Chloroquine Enhances Gefitinib Cytotoxicity in Gefitinib-Resistant Nonsmall Cell Lung Cancer Cells

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), including gefitinib, are effective for non-small cell lung cancer (NSCLC) patients with EGFR mutations. However, these patients eventually develop resistance to EGFR-TKI. The goal of the present study was to investigate the inv...

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Detalles Bibliográficos
Autores principales: Tang, Mei-Chuan, Wu, Mei-Yi, Hwang, Ming-Hung, Chang, Ya-Ting, Huang, Hui-Ju, Lin, Anya Maan-Yuh, Yang, James Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373825/
https://www.ncbi.nlm.nih.gov/pubmed/25807554
http://dx.doi.org/10.1371/journal.pone.0119135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373825/
https://www.ncbi.nlm.nih.gov/pubmed/25807554
http://dx.doi.org/10.1371/journal.pone.0119135

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