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Chloroquine Enhances Gefitinib Cytotoxicity in Gefitinib-Resistant Nonsmall Cell Lung Cancer Cells
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), including gefitinib, are effective for non-small cell lung cancer (NSCLC) patients with EGFR mutations. However, these patients eventually develop resistance to EGFR-TKI. The goal of the present study was to investigate the inv...
Autores principales: | Tang, Mei-Chuan, Wu, Mei-Yi, Hwang, Ming-Hung, Chang, Ya-Ting, Huang, Hui-Ju, Lin, Anya Maan-Yuh, Yang, James Chih-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373825/ https://www.ncbi.nlm.nih.gov/pubmed/25807554 http://dx.doi.org/10.1371/journal.pone.0119135 |
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