The Highly Conserved Codon following the Slippery Sequence Supports −1 Frameshift Efficiency at the HIV-1 Frameshift Site

HIV-1 utilises −1 programmed ribosomal frameshifting to translate structural and enzymatic domains in a defined proportion required for replication. A slippery sequence, U UUU UUA, and a stem-loop are well-defined RNA features modulating −1 frameshifting in HIV-1. The GGG glycine codon immediately f...

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Detalles Bibliográficos
Autores principales: Mathew, Suneeth F., Crowe-McAuliffe, Caillan, Graves, Ryan, Cardno, Tony S., McKinney, Cushla, Poole, Elizabeth S., Tate, Warren P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373837/
https://www.ncbi.nlm.nih.gov/pubmed/25807539
http://dx.doi.org/10.1371/journal.pone.0122176

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