Longitudinal Changes in Plasma Caspase-1 and Caspase-3 during the First 2 Years of HIV-1 Infection in CD4(Low) and CD4(High) Patient Groups

Over 95% of CD4 cell death occurs by Caspase-1-mediated pyroptosis during HIV infection. Caspase-3-mediated apoptosis accounts for the death in a small proportion of infected CD4 cells. To date, there have been no reports on the dynamics of Caspase-1 and Caspase-3 and their relationship with disease...

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Detalles Bibliográficos
Autores principales: Song, Jingjing, Jiao, Yanmei, Zhang, Tong, Zhang, Yonghong, Huang, Xiaojie, Li, Hongjun, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373860/
https://www.ncbi.nlm.nih.gov/pubmed/25806508
http://dx.doi.org/10.1371/journal.pone.0121011

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