Population Genomic Analysis of 962 Whole Genome Sequences of Humans Reveals Natural Selection in Non-Coding Regions

Whole genome analysis in large samples from a single population is needed to provide adequate power to assess relative strengths of natural selection across different functional components of the genome. In this study, we analyzed next-generation sequencing data from 962 European Americans, and foun...

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Detalles Bibliográficos
Autores principales: Yu, Fuli, Lu, Jian, Liu, Xiaoming, Gazave, Elodie, Chang, Diana, Raj, Srilakshmi, Hunter-Zinck, Haley, Blekhman, Ran, Arbiza, Leonardo, Van Hout, Cris, Morrison, Alanna, Johnson, Andrew D., Bis, Joshua, Cupples, L. Adrienne, Psaty, Bruce M., Muzny, Donna, Yu, Jin, Gibbs, Richard A., Keinan, Alon, Clark, Andrew G., Boerwinkle, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373932/
https://www.ncbi.nlm.nih.gov/pubmed/25807536
http://dx.doi.org/10.1371/journal.pone.0121644

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