Cargando…

The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System

The development and regeneration of myelin by oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), requires profound changes in cell shape that lead to myelin sheath initiation and formation. Here, we demonstrate a requirement for the basal polarity complex protein Scribbl...

Descripción completa

Detalles Bibliográficos
Autores principales: Jarjour, Andrew A., Boyd, Amanda, Dow, Lukas E., Holloway, Rebecca K., Goebbels, Sandra, Humbert, Patrick O., Williams, Anna, ffrench-Constant, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373955/
https://www.ncbi.nlm.nih.gov/pubmed/25807062
http://dx.doi.org/10.1371/journal.pbio.1002107