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The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System
The development and regeneration of myelin by oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), requires profound changes in cell shape that lead to myelin sheath initiation and formation. Here, we demonstrate a requirement for the basal polarity complex protein Scribbl...
Autores principales: | Jarjour, Andrew A., Boyd, Amanda, Dow, Lukas E., Holloway, Rebecca K., Goebbels, Sandra, Humbert, Patrick O., Williams, Anna, ffrench-Constant, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373955/ https://www.ncbi.nlm.nih.gov/pubmed/25807062 http://dx.doi.org/10.1371/journal.pbio.1002107 |
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