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Increased Mitochondrial Fission and Volume Density by Blocking Glutamate Excitotoxicity Protect Glaucomatous Optic Nerve Head Astrocytes

Abnormal structure and function of astrocytes have been observed within the lamina cribrosa region of the optic nerve head (ONH) in glaucomatous neurodegeneration. Glutamate excitotoxicity-mediated mitochondrial alteration has been implicated in experimental glaucoma. However, the relationships amon...

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Detalles Bibliográficos
Autores principales:	Ju, Won-Kyu, Kim, Keun-Young, Noh, You Hyun, Hoshijima, Masahiko, Lukas, Thomas J, Ellisman, Mark H, Weinreb, Robert N, Perkins, Guy A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373968/ https://www.ncbi.nlm.nih.gov/pubmed/25557093 http://dx.doi.org/10.1002/glia.22781

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