Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity

GABA transporters control extracellular GABA, which regulates the key aspects of neuronal and network behaviour. A prevailing view is that modest neuronal depolarization results in GABA transporter type-1 (GAT-1) reversal causing non-vesicular GABA release into the extracellular space during intense...

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Detalles Bibliográficos
Autores principales: Savtchenko, Leonid, Megalogeni, Maria, Rusakov, Dmitri A., Walker, Matthew C., Pavlov, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374149/
https://www.ncbi.nlm.nih.gov/pubmed/25798861
http://dx.doi.org/10.1038/ncomms7597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374149/
https://www.ncbi.nlm.nih.gov/pubmed/25798861
http://dx.doi.org/10.1038/ncomms7597

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