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SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells

BACKGROUND: Tumor metastasis is responsible for 90% of cancer-related deaths. Recently, a strong link between microRNA dysregulation and human cancers has been established. However, the molecular mechanisms through which microRNAs regulate metastasis and cancer progression remain unclear. METHODS: W...

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Detalles Bibliográficos
Autores principales: Koumangoye, Rainelli B, Andl, Thomas, Taubenslag, Kenneth J, Zilberman, Steven T, Taylor, Chase J, Loomans, Holli A, Andl, Claudia D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374188/
https://www.ncbi.nlm.nih.gov/pubmed/25644061
http://dx.doi.org/10.1186/s12943-014-0284-y