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P2X receptors trigger intracellular alkalization in isolated perfused mouse medullary thick ascending limb

AIMS: Extracellular ATP is an important regulator of renal tubular transport. Recently, we found that basolateral ATP markedly inhibits Na(+) and Cl(−) absorption in mouse medullary thick ascending limb (mTAL) via a P2X receptor. The underlying mechanism that mediates this ATP-dependent transport in...

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Detalles Bibliográficos
Autores principales:	de Bruijn, P I A, Bleich, M, Praetorius, H A, Leipziger, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Special Series on Renal Purinergic Signalling in Health and Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374443/ https://www.ncbi.nlm.nih.gov/pubmed/25362991 http://dx.doi.org/10.1111/apha.12417

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