Loss of dysbindin-1, a risk gene for schizophrenia, leads to impaired group 1 metabotropic glutamate receptor function in mice

The expression of dysbindin-1, a protein coded by the risk gene dtnbp1, is reduced in the brains of schizophrenia patients. Evidence indicates a role of dysbindin-1 in dopaminergic and glutamatergic transmission. Glutamatergic transmission and plasticity at excitatory synapses is critically regulate...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Sanjeev K., Ryan, Richard T., Wong, Tak Pan, Srivastava, Lalit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374471/
https://www.ncbi.nlm.nih.gov/pubmed/25859193
http://dx.doi.org/10.3389/fnbeh.2015.00072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374471/
https://www.ncbi.nlm.nih.gov/pubmed/25859193
http://dx.doi.org/10.3389/fnbeh.2015.00072

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