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Frequencies of Gag-restricted T-cell escape “footprints” differ across HIV-1 clades A1 and D chronically infected Ugandans irrespective of host HLA B alleles()
OBJECTIVE(S): We evaluated relationships between critical Gag T-cell escape mutations and concomitant T-cell responses to determine whether HLA-restricted Gag mutations that confer protection, occur at similar rates in a population infected with mixed HIV-1 clades A1 and D viruses. METHODS: Assessme...
Autores principales: | Serwanga, Jennifer, Nakiboneka, Ritah, Mugaba, Susan, Magambo, Brian, Ndembi, Nicaise, Gotch, Frances, Kaleebu, Pontiano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374673/ https://www.ncbi.nlm.nih.gov/pubmed/25728323 http://dx.doi.org/10.1016/j.vaccine.2015.02.037 |
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