Cargando…

Hydrogen Sulfide Regulates the Colonic Motility by Inhibiting Both L-Type Calcium Channels and BK(Ca) Channels in Smooth Muscle Cells of Rat Colon

OBJECTIVE: To examine the hypothesis that hydrogen sulfide (H(2)S) regulates the colonic motility by modulating both L-type voltage-dependent calcium channels and large conductance Ca(2+)-activated K(+) (BK(Ca)) channels. METHODS: Immunohistochemistry was performed on rat colonic samples to investig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quan, Xiaojing, Luo, Hesheng, Liu, Yin, Xia, Hong, Chen, Wei, Tang, Qincai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374679/ https://www.ncbi.nlm.nih.gov/pubmed/25811907 http://dx.doi.org/10.1371/journal.pone.0121331

Ejemplares similares

Hydrogen Sulfide Relaxes Human Uterine Artery via Activating Smooth Muscle BK(Ca) Channels
por: Li, Yan, et al.
Publicado: (2020)

Role of BK(Ca) in Stretch-Induced Relaxation of Colonic Smooth Muscle
por: Ren, Jie, et al.
Publicado: (2016)

Phosphorylation of BK channels modulates the sensitivity to hydrogen sulfide (H(2)S)
por: Sitdikova, Guzel F., et al.
Publicado: (2014)

Actions of Hydrogen Sulfide and ATP-Sensitive Potassium Channels on Colonic Hypermotility in a Rat Model of Chronic Stress
por: Liu, Ying, et al.
Publicado: (2013)

Mitochondrial BK(Ca) channel
por: Balderas, Enrique, et al.
Publicado: (2015)

BK(Ca) Channels as Targets for Cardioprotection
por: Szteyn, Kalina, et al.
Publicado: (2020)

Regulation of colonic apical potassium (BK) channels by cAMP and somatostatin
por: Perry, M. D., et al.
Publicado: (2009)

BK(Ca) channel dysfunction in neurological diseases
por: N'Gouemo, Prosper
Publicado: (2014)

Regulatory mechanisms of mitochondrial BK(Ca) channels
por: González-Cota, Ana L., et al.
Publicado: (2021)

Measuring the Influence of the BK(Ca) β1 Subunit on Ca(2+) Binding to the BK(Ca) Channel
por: Sweet, Tara-Beth, et al.
Publicado: (2009)

Impaired BK(Ca) channel function in native vascular smooth muscle from humans with type 2 diabetes
por: Nieves-Cintrón, Madeline, et al.
Publicado: (2017)

T-type calcium channel modulation by hydrogen sulfide in neuropathic pain conditions
por: Rangel-Galván, Maricruz, et al.
Publicado: (2023)

Hydrogen sulfide-induced itch requires activation of Ca(v)3.2 T-type calcium channel in mice
por: Wang, Xue-Long, et al.
Publicado: (2015)

Ca(2+) block and flickering both contribute to the negative slope of the IV curve in BK channels
por: Schroeder, Indra, et al.
Publicado: (2013)

Bidirectional TRP/L Type Ca(2+) Channel/RyR/BK(Ca) Molecular and Functional Signaloplex in Vascular Smooth Muscles
por: Dryn, Dariia O., et al.
Publicado: (2023)

Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021
por: Rockman, Michael E., et al.
Publicado: (2020)

BK Channel News: Full Coverage on the Calcium Bowl
por: Moczydlowski, Edward G.
Publicado: (2004)

Elimination of the BK(Ca) Channel's High-Affinity Ca(2+) Sensitivity
por: Bao, Lin, et al.
Publicado: (2002)

Corrigendum: Hydrogen sulfide-induced itch requires activation of Ca(v)3.2 T-type calcium channel in mice
por: Wang, Xue-Long, et al.
Publicado: (2017)

Effect of visfatin on K(ATP) channel upregulation in colonic smooth muscle cells in diabetic colon dysmotility
por: Yu, Ting, et al.
Publicado: (2022)

Estrogen inhibits colonic smooth muscle contractions by regulating BKβ1 signaling
por: Wen, Jing, et al.
Publicado: (2023)

Modes of Operation of the BK(Ca) Channel β(2) Subunit
por: Savalli, Nicoletta, et al.
Publicado: (2007)

Intra- and Intersubunit Cooperativity in Activation of BK Channels by Ca(2+)
por: Qian, Xiang, et al.
Publicado: (2006)

Where’s the gate? Gating in the deep pore of the BK(Ca) channel
por: Cox, Daniel H., et al.
Publicado: (2011)

Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels
por: Oh, Kelly H, et al.
Publicado: (2015)

Permissive Modulation of Sphingosine-1-Phosphate-Enhanced Intracellular Calcium on BK(Ca) Channel of Chromaffin Cells
por: Wu, Adonis Z., et al.
Publicado: (2021)

The Na(v)1.9 channel regulates colonic motility in mice
por: Copel, Carine, et al.
Publicado: (2013)

Proximal clustering between BK and Ca(V)1.3 channels promotes functional coupling and BK channel activation at low voltage
por: Vivas, Oscar, et al.
Publicado: (2017)

Oxidative Stress and Maxi Calcium-Activated Potassium (BK) Channels
por: Hermann, Anton, et al.
Publicado: (2015)

Calcium-driven regulation of voltage-sensing domains in BK channels
por: Lorenzo-Ceballos, Yenisleidy, et al.
Publicado: (2019)

Natural Bile Acids and Synthetic Analogues Modulate Large Conductance Ca(2+)-activated K(+) (BK(Ca)) Channel Activity in Smooth Muscle Cells
por: Dopico, Alejandro M., et al.
Publicado: (2002)

A junctophilin-caveolin interaction enables efficient coupling between ryanodine receptors and BK(Ca) channels in the Ca(2+) microdomain of vascular smooth muscle
por: Saeki, Takanori, et al.
Publicado: (2019)

Light-Mediated Inhibition of Colonic Smooth Muscle Constriction and Colonic Motility via Opsin 3
por: Dan, William, et al.
Publicado: (2021)

Structural and Functional Coupling of Calcium-Activated BK Channels and Calcium-Permeable Channels Within Nanodomain Signaling Complexes
por: Shah, Kunal R., et al.
Publicado: (2022)

Type 1 IP(3) receptors activate BK(Ca) channels via local molecular coupling in arterial smooth muscle cells
por: Zhao, Guiling, et al.
Publicado: (2010)

Extra Virgin Olive Oil Phenols Dilate the Rat Mesenteric Artery by Activation of BK(Ca2+) Channels in Smooth Muscle Cells
por: D’Agostino, Rossana, et al.
Publicado: (2020)

Involvement of K(+)(ATP) and Ca(2+) channels in hydrogen sulfide-suppressed ageing of porcine oocytes
por: Nevoral, Jan, et al.
Publicado: (2018)

Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells
por: Qian, Ling-Ling, et al.
Publicado: (2018)

Lack of direct effect of adiponectin on vascular smooth muscle cell BK(Ca) channels or Ca(2+) signaling in the regulation of small artery pressure‐induced constriction
por: Baylie, Rachael, et al.
Publicado: (2017)

The BK(Ca) Channel's Ca(2+)-binding Sites, Multiple Sites, Multiple Ions
por: Cox, Daniel H.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_u2ft366pno3f62jvprca98b2dh