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Host APOBEC3G Protein Inhibits HCV Replication through Direct Binding at NS3
Human APOBEC3G (hA3G) is a cytidine deaminase that restricts replication of certain viruses. We have previously reported that hA3G was a host restriction factor against hepatitis C virus (HCV) replication, and hA3G stabilizers showed a significant inhibitory activity against HCV. However, the molecu...
Autores principales: | Zhu, Yan-Ping, Peng, Zong-Gen, Wu, Zhou-Yi, Li, Jian-Rui, Huang, Meng-Hao, Si, Shu-Yi, Jiang, Jian-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374698/ https://www.ncbi.nlm.nih.gov/pubmed/25811715 http://dx.doi.org/10.1371/journal.pone.0121608 |
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