Markedly Increased IP-10 Production by Blood-Brain Barrier in Neuromyelitis Optica

OBJECTIVE: Severe damage to the blood-brain barrier (BBB) allows anti-aquaporin 4 (AQP4) antibodies to access the astrocytic endfeet in neuromyelitis optica (NMO). In the current study, we identified the pathogenic cytokines/chemokines that are responsible for the BBB malfunction induced by NMO sera...

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Detalles Bibliográficos
Autores principales: Shimizu, Fumitaka, Nishihara, Hideaki, Sano, Yasuteru, Takeshita, Yukio, Takahashi, Shiori, Maeda, Toshihiko, Takahashi, Toshiyuki, Abe, Masaaki, Koga, Michiaki, Kanda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374747/
https://www.ncbi.nlm.nih.gov/pubmed/25811465
http://dx.doi.org/10.1371/journal.pone.0122000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374747/
https://www.ncbi.nlm.nih.gov/pubmed/25811465
http://dx.doi.org/10.1371/journal.pone.0122000

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