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Involvement of DNA-PKcs in the Type I IFN Response to CpG-ODNs in Conventional Dendritic Cells in TLR9-Dependent or -Independent Manners

CpG-ODNs activate dendritic cells (DCs) to produce interferon alpha (IFNα) and beta (IFNβ). Previous studies demonstrated that Toll-like receptor 9 (TLR9) deficient DCs exhibited a residual IFNα response to CpG-A, indicating that yet-unidentified molecules are also involved in induction of IFNα by C...

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Detalles Bibliográficos
Autores principales:	Ma, Chi, Spies, Narrissa P., Gong, Ting, Jones, Can Xin, Chu, Wen-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374755/ https://www.ncbi.nlm.nih.gov/pubmed/25812014 http://dx.doi.org/10.1371/journal.pone.0121371

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