All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear

The kinase Akt is a key downstream mediator of the phosphoinositide-3-kinase signaling pathway and participates in a variety of cellular processes. Akt comprises three isoforms each encoded by a separate gene. There is evidence to indicate that Akt is involved in the survival and protection of audit...

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Detalles Bibliográficos
Autores principales: Brand, Yves, Levano, Soledad, Radojevic, Vesna, Naldi, Arianne Monge, Setz, Cristian, Ryan, Allen F., Pak, Kwang, Hemmings, Brian A., Bodmer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374771/
https://www.ncbi.nlm.nih.gov/pubmed/25811375
http://dx.doi.org/10.1371/journal.pone.0121599

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