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New Insights on the Mechanism of the K(+)-Independent Activity of Crenarchaeota Pyruvate Kinases
Eukarya pyruvate kinases have glutamate at position 117 (numbered according to the rabbit muscle enzyme), whereas in Bacteria have either glutamate or lysine and in Archaea have other residues. Glutamate at this position makes pyruvate kinases K(+)-dependent, whereas lysine confers K(+)-independence...
Autores principales: | De la Vega-Ruíz, Gustavo, Domínguez-Ramírez, Lenin, Riveros-Rosas, Héctor, Guerrero-Mendiola, Carlos, Torres-Larios, Alfredo, Hernández-Alcántara, Gloria, García-Trejo, José J., Ramírez-Silva, Leticia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374775/ https://www.ncbi.nlm.nih.gov/pubmed/25811853 http://dx.doi.org/10.1371/journal.pone.0119233 |
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