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Tertiary siRNAs Mediate Paramutation in C. elegans

In the nematode Caenorhabditis elegans, different small RNA-dependent gene silencing mechanisms act in the germline to initiate transgenerational gene silencing. Piwi-interacting RNAs (piRNAs) can initiate transposon and gene silencing by acting upstream of endogenous short interfering RNAs (siRNAs)...

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Detalles Bibliográficos
Autores principales:	Sapetschnig, Alexandra, Sarkies, Peter, Lehrbach, Nicolas J., Miska, Eric A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374809/ https://www.ncbi.nlm.nih.gov/pubmed/25811365 http://dx.doi.org/10.1371/journal.pgen.1005078

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