A Voltage-Gated Calcium Channel Regulates Lysosomal Fusion with Endosomes and Autophagosomes and Is Required for Neuronal Homeostasis

Autophagy helps deliver sequestered intracellular cargo to lysosomes for proteolytic degradation and thereby maintains cellular homeostasis by preventing accumulation of toxic substances in cells. In a forward mosaic screen in Drosophila designed to identify genes required for neuronal function and...

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Detalles Bibliográficos
Autores principales: Tian, Xuejun, Gala, Upasana, Zhang, Yongping, Shang, Weina, Nagarkar Jaiswal, Sonal, di Ronza, Alberto, Jaiswal, Manish, Yamamoto, Shinya, Sandoval, Hector, Duraine, Lita, Sardiello, Marco, Sillitoe, Roy V., Venkatachalam, Kartik, Fan, Hengyu, Bellen, Hugo J., Tong, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374850/
https://www.ncbi.nlm.nih.gov/pubmed/25811491
http://dx.doi.org/10.1371/journal.pbio.1002103

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