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The Novel Tubulin Polymerization Inhibitor MHPT Exhibits Selective Anti-Tumor Activity against Rhabdomyosarcoma In Vitro and In Vivo

The dose-limiting toxicity caused by standard chemotherapy has become a major roadblock to successful rhabdomyosarcoma chemotherapy. By screening a thiazolidinone library including 372 compounds, a novel synthetic compound, 2-((4-hydroxyphenyl)imino)-5-(3-methoxybenzylidene)thiazolidin-4-one (MHPT),...

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Detalles Bibliográficos
Autores principales:	Mu, Yan, Liu, Yin, Li, Liwen, Tian, Cong, Zhou, Hongyu, Zhang, Qiu, Yan, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374867/ https://www.ncbi.nlm.nih.gov/pubmed/25811876 http://dx.doi.org/10.1371/journal.pone.0121806

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