Variations in the Binding Pocket of an Inhibitor of the Bacterial Division Protein FtsZ across Genotypes and Species

The recent increase in antibiotic resistance in pathogenic bacteria calls for new approaches to drug-target selection and drug development. Targeting the mechanisms of action of proteins involved in bacterial cell division bypasses problems associated with increasingly ineffective variants of older...

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Detalles Bibliográficos
Autores principales: Miguel, Amanda, Hsin, Jen, Liu, Tianyun, Tang, Grace, Altman, Russ B., Huang, Kerwyn Casey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374959/
https://www.ncbi.nlm.nih.gov/pubmed/25811761
http://dx.doi.org/10.1371/journal.pcbi.1004117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374959/
https://www.ncbi.nlm.nih.gov/pubmed/25811761
http://dx.doi.org/10.1371/journal.pcbi.1004117

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