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Effect of Phosphorylation on EGFR Dimer Stability Probed by Single-Molecule Dynamics and FRET/FLIM

Deregulation of epidermal growth factor receptor (EGFR) signaling has been correlated with the development of a variety of human carcinomas. EGF-induced receptor dimerization and consequent trans- auto-phosphorylation are among the earliest events in signal transduction. Binding of EGF is thought to...

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Detalles Bibliográficos
Autores principales:	Coban, Oana, Zanetti-Dominguez, Laura C., Matthews, Daniel R., Rolfe, Daniel J., Weitsman, Gregory, Barber, Paul R., Barbeau, Jody, Devauges, Viviane, Kampmeier, Florian, Winn, Martyn, Vojnovic, Borivoj, Parker, Peter J., Lidke, Keith A., Lidke, Diane S., Ameer-Beg, Simon M., Martin-Fernandez, Marisa L., Ng, Tony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2015
Materias:	Cell Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375452/ https://www.ncbi.nlm.nih.gov/pubmed/25762314 http://dx.doi.org/10.1016/j.bpj.2015.01.005

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