Cargando…
Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins
Human induced pluripotent stem cells (hiPSCs), like embryonic stem cells, are under intense investigation for novel approaches to model disease and for regenerative therapies. Here, we describe the derivation and characterization of hiPSCs from a variety of sources and show that, irrespective of ori...
Autores principales: | Yang, Cheng-Tao, French, Anna, Goh, Pollyanna Agnes, Pagnamenta, Alistair, Mettananda, Sachith, Taylor, Jenny, Knight, Sam, Nathwani, Amit, Roberts, David J, Watt, Suzanne M, Carpenter, Lee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375519/ https://www.ncbi.nlm.nih.gov/pubmed/24837254 http://dx.doi.org/10.1111/bjh.12910 |
Ejemplares similares
-
Iron overload across the spectrum of non‐transfusion‐dependent thalassaemias: role of erythropoiesis, splenectomy and transfusions
por: Porter, John B., et al.
Publicado: (2016) -
An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin
por: Carrancio, Soraya, et al.
Publicado: (2014) -
Vesicular formation regulated by ERK/MAPK pathway mediates human erythroblast enucleation
por: An, Chao, et al.
Publicado: (2021) -
Plasmodium falciparum infection of human erythroblasts induces transcriptional changes associated with dyserythropoiesis
por: Feldman, Tamar P., et al.
Publicado: (2023) -
Germline ERCC excision repair 6 like 2 (
ERCC6L2
) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment
por: Armes, Hannah, et al.
Publicado: (2022)