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The BET Family Member BRD4 Interacts with OCT4 and Regulates Pluripotency Gene Expression
Embryonic stem cell (ESC) pluripotency is controlled by defined transcription factors. During cellular differentiation, ESCs undergo a global epigenetic reprogramming. Female ESCs exemplify this process as one of the two X-chromosomes is globally silenced during X chromosome inactivation (XCI) to ba...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375790/ https://www.ncbi.nlm.nih.gov/pubmed/25684227 http://dx.doi.org/10.1016/j.stemcr.2015.01.012 |