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Enhanced Hematopoietic Stem Cell Function Mediates Immune Regeneration following Sex Steroid Blockade

Mechanisms underlying age-related defects within lymphoid-lineages remain poorly understood. We previously reported that sex steroid ablation (SSA) induced lymphoid rejuvenation and enhanced recovery from hematopoietic stem cell (HSC) transplantation (HSCT). We herein show that, mechanistically, SSA...

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Detalles Bibliográficos
Autores principales:	Khong, Danika M., Dudakov, Jarrod A., Hammett, Maree V., Jurblum, Marc I., Khong, Sacha M.L., Goldberg, Gabrielle L., Ueno, Tomoo, Spyroglou, Lisa, Young, Lauren F., van den Brink, Marcel R.M., Boyd, Richard L., Chidgey, Ann P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375937/ https://www.ncbi.nlm.nih.gov/pubmed/25733018 http://dx.doi.org/10.1016/j.stemcr.2015.01.018

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