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A practical guide to genetic engineering of pancreatic β-cells in vivo: Getting a grip on RIP and MIP
In vivo gene manipulation is a cornerstone approach in modern physiology. Cre-Lox technology has been extensively used to delete genes and activate reporters in pancreatic β-cells, bringing new insight into the pathophysiology of diabetes. In all cases, it is important to understand the expression d...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376052/ https://www.ncbi.nlm.nih.gov/pubmed/25322827 http://dx.doi.org/10.4161/19382014.2014.944439 |