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A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland

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Progesterone drives mammary stem and progenitor cell dynamics through paracrine mechanisms that are currently not well understood. Here, we demonstrate that CXCR4, the receptor for stromal-derived factor 1 (SDF-1; CXC12), is a crucial instructor of hormone-induced mammary stem and progenitor cell fu...

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Detalles Bibliográficos
Autores principales:	Shiah, Yu-Jia, Tharmapalan, Pirashaanthy, Casey, Alison E., Joshi, Purna A., McKee, Trevor D., Jackson, Hartland W., Beristain, Alexander G., Chan-Seng-Yue, Michelle A., Bader, Gary D., Lydon, John P., Waterhouse, Paul D., Boutros, Paul C., Khokha, Rama
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376056/ https://www.ncbi.nlm.nih.gov/pubmed/28447939 http://dx.doi.org/10.1016/j.stemcr.2015.01.011

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